Award
National Institute of Allergy and Infectious Diseases R21AI195355-01
Dual-Activity Inhibitors Targeting Aspergillus fumigatus PanK for Antifungal Therapy
Recipient
Yale University
Award Amount
$283,926.00
Ceiling
$283,926.00
Awarded
May 07, 2026
Identifier
R21AI195355-01
This NIH grant supports research at Yale University to develop and evaluate dual-activity inhibitors targeting Aspergillus fumigatus PanK for antifungal therapy, with a total award amount of approximately $283,926 for fiscal year 2026.
Description
The project focuses on developing small-molecule inhibitors of A. fumigatus pantothenate kinase. The project aims to evaluate biochemical activity, pharmacological properties, and efficacy of compounds. The project includes screening compounds against clinical isolates and testing in animal models.