Award
NIH Reporter #2R01GM054712-27A1
Polarized Exocytosis: Rabs, Tethers, and SNAREs
Recipient
UNIV OF NORTH CAROLINA CHAPEL HILL
Award Amount
$457,456.00
Ceiling
$457,456.00
Awarded
August 21, 2025
Identifier
2R01GM054712-27A1
Research project funded by NIH to study cellular mechanisms of polarized exocytosis and cell polarity, with implications for cancer and diabetes treatment.
Description
Investigation into the fundamental mechanisms by which cells direct polarized growth, relevant to understanding diseases including tumor development and Type II diabetes. The project aims to understand regulation and coordination of exocytosis and cell polarity, focusing on molecular mechanisms involving Rho/Cdc42 GTPases, the exocyst, and Sro7/Tomosyn family members.