Award

National Institute of General Medical Sciences 2R35GM138211-06

Harnessing protein clustering to understand, identify, and manipulate cellular systems

Recipient

University of Pennsylvania

Award Amount

$536,106.00

Ceiling

$536,106.00

Awarded

July 01, 2025

Identifier

2R35GM138211-06

A grant awarded to develop optogenetic tools and synthetic protein therapies based on protein clustering to manipulate cellular systems and treat diseases such as neurodegeneration, viral infections, and cancer.

Description

The project aims to develop technologies exploiting protein clustering to manipulate cells, including light-activated probes and engineered protein systems for disease detection and response, with applications in neurodegeneration, viral infections, and cancer.

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