Award
NIH Reporter #11372226
PI3K Beta regulation of tumor metastasis
Recipient
Albert Einstein College of Medicine
Award Amount
$469,093.00
Ceiling
$469,093.00
Awarded
June 26, 2026
Identifier
11372226
NIH grant awarded to Albert Einstein College of Medicine to study PI3Kβ's role in breast cancer metastasis, focusing on tumor cell interactions with macrophages and platelets to improve metastatic disease treatments.
Description
This NIH grant project investigates the role of Class I PI3K, specifically PI3Kβ, in regulating breast cancer metastasis through interactions between tumor cells, macrophages, and platelets. The study aims to understand mechanisms of tumor metastasis and provide preclinical data supporting PI3Kβ inhibitors for metastatic disease treatment.