Award
National Institute of Allergy and Infectious Diseases 5R16AI175022-04
Effects of estrus cycle stages on murine CDI severity
Recipient
University of Nevada Las Vegas
Award Amount
$145,790.00
Ceiling
$145,790.00
Awarded
June 23, 2026
Identifier
5R16AI175022-04
A research project funded by the National Institute of Allergy and Infectious Diseases to study how estrus cycle stages and sex hormone levels affect the severity of Clostridium difficile infection in mice, aiming to inform future research on sex differences in CDI susceptibility.
Description
This project aims to test the effect of estrus cycle and sex hormone levels on Clostridium difficile infection (CDI) onset and severity using a murine model. The study will investigate the role of sex hormones in CDI severity and susceptibility, helping to understand sex differences in CDI susceptibility.