Award
National Cancer Institute 5R01CA290724-03
Cellular basis for cancer treatment related GDF15 expression and the regulation of skeletal muscle fibrosis and neuromuscular integrity.
Recipient
Duke University
Award Amount
$583,677.00
Ceiling
$583,677.00
Awarded
March 05, 2026
Identifier
5R01CA290724-03
This NIH grant awarded to Duke University supports research on the cellular mechanisms of cancer treatment-related GDF15 expression and its impact on skeletal muscle fibrosis and neuromuscular integrity, aiming to find interventions for neuromuscular decline in pediatric cancer survivors.
Description
The project focuses on the role of GDF15 and Ret in neuromuscular decline post pediatric cancer treatment. The project involves multiple methodologies including gene expression analysis, imaging, and pharmacological treatments. The project aims to identify interventions to mitigate neuromuscular decline in pediatric cancer survivors.