Award
National Eye Institute 5R01EY033003-04
Development and application of a high-fidelity computational model of diabetic retinopathy hemodynamics: Coupling single-cell biophysics with retinal vascular network topology and complexity
Recipient
Rutgers, The State University of New Jersey
Award Amount
$337,450.00
Ceiling
$337,450.00
Awarded
July 22, 2024
Identifier
5R01EY033003-04
The award funds the development of a multiscale computational model to study diabetic retinopathy hemodynamics by integrating retinal vascular geometry and blood cell biophysics to predict disease progression and vascular abnormalities.
Description
This project will develop a computer model to predict initiation and progression of diabetic retinopathy based on changes in blood flow in retinal vessels caused by changes in blood cell properties and vessel structure due to prolonged diabetic conditions. The model aims to provide insights into blood flow-mediated pathogenesis and metrics for early detection, benefiting clinical diagnosis and treatment.