Award
National Institute of Neurological Disorders and Stroke 5R33NS126618-03
Evaluation of a specific LXR/PPAR agonist for treatment of Alzheimer's disease
Recipient
National Institute of Neurological Disorders and Stroke (NINDS), NIH
Award Amount
$344,798.00
Ceiling
$344,798.00
Awarded
February 19, 2026
Identifier
5R33NS126618-03
This award funds research to evaluate the safety and efficacy of a specific LXR/PPAR agonist for treating Alzheimer's disease using a mouse model.
Description
The project aims to determine the optimal dose of a selective LXRβ/PPAR agonist, AU403, for safety and efficacy in an Alzheimer's disease mouse model, positioning this compound as a potential preventive and/or treatment for Alzheimer's disease and related dementias.