Award
National Institute on Aging 5U01AG088557-02
PRE3BAD: Preclinical Research on Emerging Environmental Exposures, Brain Aging, and Dementia
Recipient
University of New Mexico Health Sciences Center
Award Amount
$1,896,687.00
Ceiling
$1,896,687.00
Awarded
August 13, 2025
Identifier
5U01AG088557-02
A research project funded by the National Institute on Aging to study the effects of environmental pollutants on brain aging and dementia using mouse models, integrating multi-omic data to understand disease progression.
Description
This project assesses the neuropathological impacts of environmental contaminants such as wildfire smoke, microplastics, and heavy metals in mouse models of Alzheimer's disease and related dementias. It aims to characterize multi-omic pathways affected by these exposures and identify pathways that exacerbate disease phenotypes using molecular and histopathological assessments.