Award
National Heart, Lung, and Blood Institute 3R33HL166441-04S1
Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent Rheumatic Heart Disease: A non-inferiority randomized trial. (GOALIE)
Recipient
Cincinnati Children's Hospital Medical Center
Award Amount
$680,919.00
Ceiling
$680,919.00
Awarded
February 20, 2026
Identifier
3R33HL166441-04S1
A randomized trial funded by NHLBI comparing intramuscular and oral penicillin prophylaxis to prevent latent rheumatic heart disease progression in children.
Description
This project involves a randomized non-inferiority trial comparing intramuscular and oral penicillin prophylaxis to prevent the progression of latent rheumatic heart disease in children, with a focus on low-resource settings. The study is funded by the NHLBI and is scheduled from 2023 to 2028.