Award
NIH Office of the Director 1K01OD038415-01A1
MAP2K2 in influenza virus-induced acute lung injury and resolution
Recipient
University of Washington
Award Amount
$122,769.00
Ceiling
$122,769.00
Awarded
June 24, 2026
Identifier
1K01OD038415-01A1
This NIH-funded project aims to study the role of MEK2 in lung injury and immune response during influenza A virus infection, with the goal of developing host-directed therapies for virus-induced lung inflammation and injury.
Description
The purpose of this K01 SERCA application is to provide the protected research time and mentorship necessary for Dr. Jourdan Brune, DVM, PhD, DACLAM, to become an independent investigator. The research focuses on host factors that exacerbate lung inflammation and injury caused by viral pathogens such as influenza A virus and SARS-CoV-2. The study investigates the role of the MEK pathway, particularly MEK2, in lung injury and recovery during viral pneumonia.