# NIH Reporter #5P01CA066996-27

Defining mechanisms of action of Menin inhibition in AML

**Recipient:** Dana-Farber Cancer Institute, Boston, MA

**Award Amount:** $389,430.00
**Ceiling:** $389,430.00

**Awarded:** September 07, 2026

**Identifier:** 5P01CA066996-27

Award for research on Menin inhibition mechanisms in AML, emphasizing chromatin and protein complex targeting with drug combinations and PROTACs.

### Description

Research project focused on epigenetic complexes involved in acute myeloid leukemia (AML), targeting chromatin structures and protein complexes with drug combinations and PROTACs. Study aims include chromatin structure analysis, protein complex composition, and stability mechanisms.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11402010)