Award
NIH Reporter #5R01HD110585-03
Preconception Maternal Nutrition, Offspring DNA Methylation, and Infant Growth in Low Resource Settings
Recipient
University of Oklahoma Health Sciences Center
Award Amount
$467,754.00
Ceiling
$467,754.00
Awarded
January 31, 2026
Identifier
5R01HD110585-03
Award for research on the impact of maternal nutrition on infant DNA methylation and growth in low resource settings, using data from a multi-country randomized controlled trial.
Description
This project tests if growth stunting and maternal nutritional status impact the epigenome of infants at birth and 3 months, and assesses if the epigenome influences infant growth in the first 2 years of life. It leverages a completed randomized controlled trial in mother-infant dyads from the Democratic Republic of the Congo, Guatemala, India, and Pakistan, involving three treatment arms with different maternal nutritional supplements.