Award
National Institute of Allergy and Infectious Diseases 5U24AI120134-10
Development of multi-modal single-cell technology to dissect epitope specificity to HIV
Recipient
Emory University, Atlanta, GA, United States
Award Amount
$1,296,133.00
Ceiling
$1,296,133.00
Awarded
May 09, 2024
Identifier
5U24AI120134-10
The award supports the development of advanced single-cell genomic technologies using DNA bar-coding to analyze immune responses to HIV, facilitating the discovery of broadly neutralizing antibodies and detailed profiling of HIV epitopes and infected cells.
Description
This project aims to develop novel tools to study immune responses against HIV at the single cell level. It will utilize DNA-bar-coding methodology to build reagents capable of resolving immune responses to different molecular structures of the HIV virus. The methods developed will accelerate the discovery of effective antibodies against HIV and enable rapid identification of viral structures against which the immune system is most effective.