Award
National Institute on Aging PA-21-049
Boosting protein synthesis using antisense oligonucleotides to treat neurodegeneration
Recipient
National Institute on Aging (NIA), part of the NIH
Award Amount
$36,570.00
Ceiling
$36,570.00
Awarded
May 19, 2026
Identifier
PA-21-049
NIH grant awarded to support research on using antisense oligonucleotides to boost protein synthesis for treating neurodegenerative diseases, focusing on TBK1 gene upregulation.
Description
This NIH grant supports research on gene upregulation strategies in the central nervous system using antisense oligonucleotides, focusing on neurodegenerative diseases such as ALS and FTD. The project aims to evaluate the efficacy of 3'UTR-targeting ASOs to stimulate protein synthesis, with a focus on TBK1 gene upregulation.