Award
NIH Reporter #1R01HL187653-01
Targeting hypothalamic astrocytes in obesity-associated hypertension
Recipient
University of Iowa
Award Amount
$622,619.00
Ceiling
$622,619.00
Awarded
August 17, 2026
Identifier
1R01HL187653-01
NIH awarded a grant to University of Iowa for research on hypothalamic astrocytes' role in obesity-associated hypertension, with a focus on imaging and chemogenetics to identify therapeutic targets.
Description
This is a NIH grant project focusing on hypothalamic astrocytes and obesity-induced hypertension. The project involves in vivo fiber photometry imaging, chemogenetics, and analysis of astrocytic Ca2+ and cAMP dynamics. The project aims to uncover mechanisms by which astrocytes contribute to hypertension in obesity and identify potential therapeutic targets.