Award
National Institute of Mental Health 5R01MH123473-05
Integrated Reward-Inflammation Model of First Onset of Major Depression in Adolescence
Recipient
Temple University of the Commonwealth, Philadelphia, PA, USA
Award Amount
$727,321.00
Ceiling
$727,321.00
Awarded
May 23, 2025
Identifier
5R01MH123473-05
Research grant awarded to study the interaction of inflammation and reward processing in adolescent depression onset.
Description
This project aims to examine bidirectional relationships between peripheral inflammation and reward function, and their joint prediction of first onset of major depression and increases in depression symptoms in adolescents aged 14-15, using a biobehavioral high-risk longitudinal design including blood draws, self-report, behavioral measures, and fMRI scans.