Award
National Cancer Institute 3U01CA264620-05S1
Mechanism of estrogen independent proliferation in ER+ breast cancer cells
Recipient
Beckman Research Institute/City of Hope, Duarte, CA, United States
Award Amount
$93,333.00
Ceiling
$93,333.00
Awarded
August 27, 2025
Identifier
3U01CA264620-05S1
Award for research on estrogen independent proliferation mechanisms in ER+ breast cancer cells to improve understanding of resistance and develop personalized treatment strategies.
Description
This project aims to develop a new mechanistic understanding of cancer cell cycle dysregulation and resistance pathways using an experimentally validated mathematical model applied to patient tumor cells, guiding personalized treatment combinations and dosing for more durable control of cancer cell proliferation in ER+ breast cancer.