Award
NIH Reporter #5R35GM148339-04
Leveraging ubiquitin-dependent regulatory mechanisms to improve proteome quality in health and disease
Recipient
Eric J Bennett
Award Amount
$590,920.00
Ceiling
$590,920.00
Awarded
February 09, 2026
Identifier
5R35GM148339-04
NIH grant awarded to support research on ubiquitin-dependent regulatory mechanisms to enhance proteome quality and address neurodegenerative disorders.
Description
This NIH grant supports research on cellular mechanisms involved in proteostasis and neurodegenerative disorders, focusing on ubiquitin ligases such as HUWE1. The project aims to develop molecular strategies to modify cellular responses to proteotoxic stress and improve cellular fitness.