Award
National Institute of General Medical Sciences 5R44GM152985-02
Optimized Ratiometric Voltage-Sensitive Dyes for Cardiac Research, Safety Pharmacology
Recipient
POTENTIOMETRIC PROBES, LLC
Award Amount
$929,918.00
Ceiling
$929,918.00
Awarded
August 27, 2024
Identifier
5R44GM152985-02
Development and commercialization of organic voltage-sensitive dyes for high-fidelity optical recording of cardiac electrical activity, enabling improved research, drug screening, and clinical applications.
Description
The project aims to develop and commercialize organic voltage-sensitive dyes (VSDs) that convert electrical signals in cardiac cells and tissues into optical signals for high-fidelity recording. The technology enables dual-wavelength ratiometric recording, eliminating motion artifacts, and is suitable for research, drug screening, and potential clinical applications.