# NIH Reporter #1K99AI201800-01

Unveiling mechanisms of RNA editing dysregulation

**Recipient:** University of California Berkeley

**Award Amount:** $120,312.00
**Ceiling:** $120,312.00

**Awarded:** August 27, 2026

**Identifier:** 1K99AI201800-01

The project investigates how viral proteins disrupt RNA editing by ADAR enzymes and how that disruption affects immune responses and disease. It aims to identify viral and host factors involved, explain their mechanisms, and explore implications for antiviral strategies and RNA-based therapies.

### Description

Project to uncover how viruses manipulate ADARs to evade host defenses, identify factors that alter RNA editing during infection, determine how they modulate ADAR activity, and examine effects on immune activation and disease outcomes.

[View original record](https://reporter.nih.gov/search/0ftClcwKYUOEq8QKPKx2lA/project-details/11437194)