Award
National Cancer Institute 5R01CA269607-05
Targeted drug delivery system to overcome blood-brain barrier and therapeutic resistance to current standard of care in Glioblastoma
Recipient
Wayne State University
Award Amount
$517,352.00
Ceiling
$517,352.00
Awarded
April 01, 2026
Identifier
5R01CA269607-05
Award for developing a targeted drug delivery system to treat glioblastoma by overcoming the blood-brain barrier and therapeutic resistance, funded by NIH/NCI with $517,352 for FY 2026.
Description
This project involves developing a targeted drug delivery system using HPßCD-Cu(DDC)2 encapsulation and chlorotoxin targeting for glioblastoma treatment, aiming to overcome blood-brain barrier and resistance issues. The project is funded by NIH/NCI under PA-20-185, with a total award amount of $517,352 for FY 2026. The project duration is from April 2023 to March 2028, with key objectives including efficacy and safety assessments of the proposed therapeutic strategies.