Award

National Cancer Institute 5U54CA221705-08

Full Research Project 1: Testing the Efficacy of an eHealth Decision Support Tool to Help Cancer Patients Make informed Decisions About Tumor Genomic Testing

Recipient

Temple University of the Commonwealth

Award Amount

$103,972.00

Ceiling

$103,972.00

Awarded

September 10, 2025

Identifier

5U54CA221705-08

This NIH-funded project by Temple University evaluates an eHealth decision support tool to aid cancer patients in making informed decisions about tumor genomic testing, aiming to reduce decisional conflict and improve communication.

Description

The project aims to evaluate the efficacy of an electronic health (eHealth) decision support tool (DST) to improve informed decision making among cancer patients regarding tumor genomic profiling (TGP). The study builds on previous randomized controlled trials (RCTs) of the Gene Pilot tool, with a revised version called Gene PilotLX. The project involves revising the tool based on formative work, conducting user testing, and then testing its impact in a fully powered RCT with 232 cancer patients across four oncology sites. Primary outcomes include decision preparedness, decisional conflict, and communication with healthcare providers. Secondary outcomes include communication with family and perceptions of TGP. The study also examines how cultural values moderate the effects of the intervention.

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