Award
National Cancer Institute 11309198
Metabolic reprogramming to boost the fitness of anti-tumor immunity against metastatic colon cancer
Recipient
Cold Spring Harbor Laboratory
Award Amount
$640,583.00
Ceiling
$640,583.00
Awarded
May 05, 2026
Identifier
11309198
Award for research on enhancing immunotherapy for metastatic colorectal cancer by targeting immune cell metabolism, funded by NIH/NCI with $640,583.
Description
This project aims to explore new ways to treat metastatic colorectal cancer (mCRC) by manipulating immune cell metabolism, focusing on activating the PPARĪ“-Cpt1a axis in CD8+ T cells to enhance immunotherapy efficacy. The project is funded by the NIH/NCI with a total award amount of $640,583, and is scheduled from April 2026 to March 2031.