Award

National Institute of Diabetes and Digestive and Kidney Diseases 1R01DK147244-01

Phenotyping and Predicting Ultrafiltration Intolerance to Guide Transitions from Continuous to Intermittent Kidney Replacement Therapy

Recipient

University of Pennsylvania

Award Amount

$792,019.00

Ceiling

$792,019.00

Awarded

May 14, 2026

Identifier

1R01DK147244-01

NIH awarded a research grant to the University of Pennsylvania to develop predictive models and monitoring tools for ultrafiltration tolerance in dialysis patients transitioning from continuous to intermittent therapy.

Description

This project focuses on developing predictive tools for ultrafiltration tolerance in dialysis patients, combining machine learning analysis of electronic health records and a prospective observational study with hemodynamic monitoring to guide transitions from continuous to intermittent kidney replacement therapy.

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