Award
NIH Reporter #11194655
HUMAN PLATELET PAR4: NOVEL ACTIVATION, INTERINDIVIDUAL VARIATION, AND NEUTROPHIL INTERACTIONS IN VIVO AND IN VITRO
Recipient
WASHINGTON UNIVERSITY
Award Amount
$509,165.00
Ceiling
$509,165.00
Awarded
January 07, 2025
Identifier
11194655
NIH grant awarded to study genetic mechanisms of platelet activation and stroke outcomes, focusing on PAR4 receptor variants and their clinical implications.
Description
This research aims to understand the molecular genetic mechanisms contributing to blood platelet reactivity and stroke outcomes, and to develop targeted therapies for ischemic vascular disease based on individual physiology. The study involves genetic analysis of PAR4 receptor variants, their role in platelet activation, and implications for stroke and hemorrhage.