Award
National Institute of General Medical Sciences 5R35GM133724-07
Cellular Systems Genetic Approaches to Understanding Regulatory Variation
Recipient
Jackson Laboratory
Award Amount
$506,220.00
Ceiling
$506,220.00
Awarded
January 22, 2026
Identifier
5R35GM133724-07
NIH grant awarded to Jackson Laboratory for research on genetic variation's impact on chromatin biology and development using cellular systems genetics.
Description
This NIH grant supports research on how natural genetic variation influences chromatin biology, cell fate, and phenotypic diversity. The project aims to elucidate the regulatory mechanisms of chromatin landscape regulation, how genetic variation impacts chromatin structure and function, and how these variations influence development and disease. The research employs cellular systems genetics using stem cells to model differentiation and gene regulation.