Award

National Cancer Institute 5R01CA232890-07

The Effectiveness of Automated Multimodal Imaging in High Grade Squamous Intraepithelial Lesions (HSIL) Diagnosis for People Living with HIV: An International Trial

Recipient

Baylor College of Medicine

Award Amount

$942,063.00

Ceiling

$942,063.00

Awarded

September 02, 2025

Identifier

5R01CA232890-07

Development of an AI-enhanced imaging system for improved diagnosis of HSIL in people living with HIV, aiming to enhance screening accuracy and efficiency in diverse clinical settings.

Description

This project aims to develop an AI-based platform to automatically identify suspicious areas in high grade squamous intraepithelial lesions (HSIL) diagnosis, creating a fully automated high-resolution anoscopy and micro-endoscope system. The system will be evaluated in diverse clinical settings in the USA and Brazil to improve accuracy, efficiency, and clinical impact, especially for novice providers, and to assess barriers to adoption in global health settings. The technology has potential applications in screening for other cancers such as oral, cervical, skin, and stomach cancers.

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