Award
NIH Reporter #2P01HL151433-06A1
Project 2 - Bergmeier
Recipient
University of California, San Diego
Award Amount
$393,868.00
Ceiling
$393,868.00
Awarded
September 03, 2026
Identifier
2P01HL151433-06A1
NIH grant awarded to University of California, San Diego to study platelet hyper-reactivity and the role of integrin αIIbβ3 in thrombotic disease, aiming to develop new detection and intervention methods.
Description
This NIH grant project focuses on studying platelet hyper-reactivity, specifically the intermediate affinity state of integrin αIIbβ3, which is hypothesized to be a major feature driving thrombotic disease. The research aims to understand the signaling mechanisms, substrate specificity, and contribution to venous thrombosis risk associated with this integrin state, with strong translational potential for clinical applications.