Award
National Institute on Aging 5K01AG066847-05
A Translational 3D Map of Hippocampal Cell Types To Drive Investigations of Alzheimer's Disease
Recipient
University of Southern California, Los Angeles, CA
Award Amount
$125,766.00
Ceiling
$125,766.00
Awarded
July 30, 2025
Identifier
5K01AG066847-05
NIH awarded a multi-year grant to the University of Southern California to create a 3D gene expression atlas of the hippocampus to aid Alzheimer's disease research, using advanced spatial transcriptomics and neuroimaging techniques.
Description
This NIH grant supports research to develop a comprehensive human hippocampus gene expression atlas (HGEA) using spatial transcriptomics and MRI data to investigate Alzheimer's disease. The project aims to bridge translational gaps between mouse models and human AD, focusing on hippocampal neuronal cell types affected by neurodegeneration.