Award
NIH Reporter #5R01DK129870-04
Hepatic fat accumulation in nonalcoholic fatty liver disease: critical regulation by kisspeptin signaling
Recipient
Rutgers Biomedical and Health Sciences, Newark, NJ, United States
Award Amount
$473,236.00
Ceiling
$473,236.00
Awarded
April 17, 2025
Identifier
5R01DK129870-04
Research project funded by NIDDK to study kisspeptin signaling in regulating liver fat and progression of nonalcoholic fatty liver disease, aiming to identify therapeutic targets.
Description
The project investigates the role of kisspeptin (KP) and its receptor KISS1R in liver fat regulation and NAFLD progression. The research aims to decipher mechanisms by which KISS1R signaling inhibits fatty liver and NASH, assess the impact of enhancing KISS1R signaling, and study clinical relevance through plasma KP levels in patients.