Award
NIH Reporter #5R01DK122071-08
RBP2 Biology and Pathobiology
Recipient
Columbia University Health Sciences, New York, NY
Award Amount
$645,762.00
Ceiling
$645,762.00
Awarded
June 09, 2026
Identifier
5R01DK122071-08
This NIH grant funds research on the role of retinol-binding protein 2 (RBP2) in intestinal hormone secretion and metabolism, aiming to understand its impact on body weight and glucose regulation.
Description
The project explores the actions of RBP2, RBP4, retinoid- and 2-MAG signaling in regulating enteroendocrine cell activities and hormone secretion, focusing on GIP and GLP-1. The goal is to understand the biochemical basis for RBP2's role in body weight maintenance, glucose response, and hepatic triglyceride levels.