Award
National Institute on Alcohol Abuse and Alcoholism 5R01AA026302-10
Molecular mechanisms of post-transplant recurrent alcoholic liver disease
Recipient
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Award Amount
$349,875.00
Ceiling
$349,875.00
Awarded
April 03, 2026
Identifier
5R01AA026302-10
NIH funded research project studying molecular mechanisms of recurrent alcoholic liver disease after transplant, focusing on ceramide synthase 6 and lipid droplet biogenesis.
Description
This project aims to investigate the role of ceramide synthase 6 in alcohol-induced lipid droplet biogenesis and as a potential diagnostic biomarker for recurrent alcoholic liver disease post-transplant. The research involves genetic mouse models and human cell lines, with a focus on lipidomics and biochemical assays.