Award
National Institute of Neurological Disorders and Stroke 5R01NS127922-04
Novel Roles of TAZ and YAP in DNA Damage Repair with 3D Genome Organization and the Therapeutic Resistance in Glioblastoma
Recipient
Mayo Clinic Arizona
Award Amount
$439,965.00
Ceiling
$439,965.00
Awarded
June 05, 2026
Identifier
5R01NS127922-04
NIH awarded a grant to Mayo Clinic Arizona for research on the roles of TAZ and YAP in DNA damage repair and therapeutic resistance in glioblastoma, aiming to develop novel pharmacological inhibitors to overcome therapy resistance.
Description
This NIH grant project focuses on glioblastoma research, DNA damage repair mechanisms, and therapeutic resistance. The project involves molecular biology, epigenomics, and pharmacological approaches to develop novel treatments targeting the YAP/TAZ pathway to overcome therapy resistance in glioblastoma.