Award
National Eye Institute 5R01EY036445-03
ER calcium handling, single cell processing, and neural circuit function in vivo
Recipient
Columbia University, New York, NY
Award Amount
$404,926.00
Ceiling
$404,926.00
Awarded
June 01, 2026
Identifier
5R01EY036445-03
Research grant to study ER calcium signaling in neurons and its effects on neural circuit function and behavior, with implications for neurodegenerative disorders.
Description
This project aims to investigate how ER calcium signaling regulates neuronal function and stability in vivo, using the Drosophila visual system as a model. The study will measure and manipulate ER calcium dynamics in motion vision circuits, assess their role in neuronal energy demands, and evaluate impacts on neural circuit activity and behavior.