Award
National Institute of Environmental Health Sciences RFA-ES-24-005
Mast Cell Activation as a Common Mechanism of Pulmonary Toxicity by Chemical Threat Agents
Recipient
SCHOOLS OF PHARMACY
Award Amount
$1,395,741.00
Ceiling
$1,395,741.00
Awarded
August 29, 2025
Identifier
RFA-ES-24-005
This NIH grant supports research on mast cell activation as a mechanism of lung toxicity from chemical threats, using mouse models and human lung-on-a-chip technology to find therapeutic targets.
Description
The project focuses on understanding the role of mast cells in lung injury caused by chemical threat agents. The research involves in vivo mouse models and a novel human lung-on-a-chip model. The project aims to identify common mechanisms across different chemical classes to develop therapeutic targets.