Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK132535-05
Elucidating and targeting beta-cell senescence and its SASP
Recipient
JOSLIN DIABETES CENTER
Award Amount
$427,500.00
Ceiling
$427,500.00
Awarded
March 31, 2026
Identifier
5R01DK132535-05
NIH grant awarded to study pancreatic beta-cell senescence and develop therapeutic interventions, funded by NIDDK with $427,500 for FY 2026.
Description
This NIH grant focuses on understanding mechanisms of pancreatic β-cell senescence and developing therapeutic strategies. The project involves studying cell autonomous and non-cell autonomous mechanisms, identifying molecular drivers, and testing pharmacological interventions such as senolytic and senomorphic drugs.