Award
National Heart, Lung, and Blood Institute 5R01HL168700-03
Linking in vivo hemodynamics with outcomes in Type B aortic dissection using 4D flow MRI
Recipient
Northwestern University, Chicago, IL, United States
Award Amount
$655,764.00
Ceiling
$655,764.00
Awarded
July 07, 2026
Identifier
5R01HL168700-03
The award funds research to improve risk stratification and clinical management of Type B aortic dissection using advanced 4D flow MRI and AI analysis, aiming to develop new hemodynamic biomarkers and enhance clinical translation.
Description
This project aims to enhance risk prediction and clinical management of Type B aortic dissection (TBAD) through advanced MRI techniques and AI analysis. It involves developing a rapid, dual-VENC TBAD MRI protocol, performing baseline and 1-year follow-up 4D flow MRI in 100 acute TBAD patients, and finetuning AI-based analysis tools for clinical translation to improve understanding of hemodynamics in TBAD and provide new biomarkers for risk assessment.