Award
NIH Reporter #3K23AI152930-05S1
Understanding HIV's impact on RR/MDR-TB development and transmission through genomics
Recipient
Boston Medical Center, Boston, MA, United States
Award Amount
$20,698.00
Ceiling
$20,698.00
Awarded
September 26, 2025
Identifier
3K23AI152930-05S1
A research project funded by NIAID to study the impact of HIV on drug-resistant tuberculosis development and transmission using genomics in South Africa, aiming to inform interventions and improve treatment outcomes.
Description
This project aims to improve understanding of the relationship between HIV, drug-resistant TB mutations, TB transmission, and clinical outcomes to better target interventions and guide treatment. It involves examining TB drug resistance over time among people living with and without HIV in South Africa, investigating compensating mutations in TB transmission, and studying TB drug resistance evolution during treatment.