Award

National Institute on Drug Abuse 5R21DA059363-03

Nucleophile-Fragment Screening for Site-Specific Covalent Ligand Discovery in Opioid Receptor Signaling

Recipient

National Institute on Drug Abuse (NIDA)

Award Amount

$190,625.00

Ceiling

$190,625.00

Awarded

March 19, 2025

Identifier

5R21DA059363-03

Award for research on chemoproteomics to identify redox-active cysteines in opioid receptor signaling and discover covalent ligands, funded by NIDA under PA-20-195.

Description

The project focuses on developing chemoproteomics approaches to identify redox-active cysteines in opioid receptor signaling. The research aims to discover small molecules for covalent ligand discovery targeting redox-active cysteines. The project is funded under PA-20-195 and involves collaboration with the Chemical Biology and Probes Study Section (CBP).

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