Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK135587-04
Mitochondrial Mechanisms Promoting Innate and Intestinal Immunity
Recipient
Yale University
Award Amount
$497,895.00
Ceiling
$497,895.00
Awarded
January 19, 2026
Identifier
5R01DK135587-04
Research project awarded to Yale University by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study mitochondrial mechanisms in innate and intestinal immunity related to inflammatory bowel disease.
Description
This project focuses on mitochondrial pathways and their role in inflammatory bowel disease (IBD), with mechanistic studies in human macrophages and mouse models. The project aims to understand how genetic variants influence innate immune responses and explore therapeutic targets.