Award

National Institute on Aging 5R01AG081393-04

A novel target in aged fracture healing

Recipient

Duke University

Award Amount

$416,042.00

Ceiling

$416,042.00

Awarded

May 11, 2026

Identifier

5R01AG081393-04

This award supports research at Duke University to improve bone fracture healing in aged populations by targeting ApoE and MuSK pathways using neutralizing antibodies and mechanistic studies.

Description

Research grant focused on investigating Apolipoprotein E (ApoE) as an age-associated inhibitor of fracture repair, exploring neutralizing antibodies to improve aged bone healing and elucidate mechanisms involving the receptor muscle-specific kinase (MuSK).

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