Award
National Institute of Allergy and Infectious Diseases 5R33AI161818-06
Combining germline-targeting, B cell immunofocusing and Env-Ab coevolution strategies to induce HIV Envelope V2-apex broadly neutralizing antibodies
Recipient
University of Pennsylvania
Award Amount
$1,606,895.00
Ceiling
$1,606,895.00
Awarded
September 02, 2025
Identifier
5R33AI161818-06
This NIH-funded project led by the University of Pennsylvania focuses on developing an HIV vaccine by inducing broadly neutralizing antibodies through innovative immunological strategies.
Description
The project aims to develop a vaccine strategy to elicit broadly neutralizing antibodies against HIV. The project involves multiple aims including isolation of bnAbs, design of immunogens, optimization of strategies, and testing in animal models.