Award
National Cancer Institute PAR-22-216
Photofrin dark effects and heme oxygenase inducers as therapeutic in mesothelioma
Recipient
University of Pennsylvania
Award Amount
$189,922.00
Ceiling
$189,922.00
Awarded
December 19, 2025
Identifier
PAR-22-216
Research project funded by the National Cancer Institute to study Photofrin and HO-1 inducers as therapies for mesothelioma, focusing on tumor control and immune response mechanisms.
Description
The project focuses on investigating the immunomodulatory effects of Photofrin and other HO-1 inducers in mesothelioma. The research aims to characterize tumor control, antitumor immunity, and mechanisms of therapeutic effects. The study involves transcriptomics and combination with immune checkpoint blockade.