Award
NIH Reporter #1R21NS131301-01A1
Electronic nicotine device systems (ENDS)-induced alterations in glutamate homeostasis: Effects on seizure susceptibility
Recipient
University of Alabama at Birmingham, Birmingham, AL, United States
Award Amount
$396,590.00
Ceiling
$396,590.00
Awarded
February 23, 2024
Identifier
1R21NS131301-01A1
Research project studying how vaping nicotine and menthol affects neuronal function and seizure susceptibility, aiming to understand the neurobiological consequences of ENDS use.
Description
This project investigates the effects of electronic nicotine delivery systems (ENDS) with nicotine and menthol on seizure susceptibility and neuronal hyperexcitability, using a rodent vapor inhalation system to study changes in glutamate regulatory proteins and neuronal function.