Award
National Institutes of Health 5R01AG034374-15
Characterizing the Behavior Profile of Healthy Cognitive Aging
Recipient
RUSH UNIVERSITY MEDICAL CENTER
Award Amount
$820,357.00
Ceiling
$820,357.00
Awarded
June 01, 2026
Identifier
5R01AG034374-15
This award funds research to precisely characterize healthy cognitive aging and distinguish it from pathologic aging using longitudinal data, neuroimaging, and biomarkers, with the goal of early prediction of cognitive decline and dementia.
Description
The proposed study aims to characterize the profile of healthy cognitive aging by linking pathologic indices to longitudinal cognitive trajectories and identifying healthy cognitive aging as residual change. It involves advanced neuroimaging, blood biomarkers, and statistical modeling based on longitudinal data from ROSMAP and other population studies to facilitate early and accurate identification of individuals at high risk of cognitive impairment.