Award
National Institute of Neurological Disorders and Stroke 5R01NS138537-02
Interactions Between Diverse Brain Cell Types Drive Aicardi-Goutieres Neuropathology
Recipient
Children's Hospital of Philadelphia, Philadelphia, PA, United States
Award Amount
$675,062.00
Ceiling
$675,062.00
Awarded
July 25, 2025
Identifier
5R01NS138537-02
This NIH research grant funds a project investigating the cellular mechanisms behind neuropathology in Aicardi-Goutieres syndrome, focusing on brain cell interactions and using advanced rodent and immune models.
Description
A research project to identify the cellular drivers of neuropathology in Aicardi-Goutieres syndrome using rodent models with patient mutations, viral targeting, and immune chimeric models.