Award
National Institute of Allergy and Infectious Diseases 1R56AI197990-01A1
Inducing Broadly Neutralizing Antibodies to Protect Against HIV
Recipient
SAN DIEGO BIOMEDICAL RESEARCH INSTITUTE
Award Amount
$809,479.00
Ceiling
$809,479.00
Awarded
June 08, 2026
Identifier
1R56AI197990-01A1
NIH funded project to develop an mRNA vaccine to induce broadly neutralizing antibodies against HIV, focusing on native membrane trimers and antibody maturation pathways in animal models.
Description
The project involves developing an mRNA-based vaccine to induce broadly neutralizing antibodies against HIV. The project aims to express native membrane trimers, induce broad and potent bNAbs, and define the maturation pathway of bNAbs in animal models.