Award
NIH Reporter #5R24AI162317-06
Population genotyping of the germline immunoglobulin repertoire in AIDS-designated rhesus macaque breeding colonies
Recipient
Emory University, Atlanta, GA, United States
Award Amount
$837,631.00
Ceiling
$837,631.00
Awarded
September 09, 2026
Identifier
5R24AI162317-06
Award for genomic sequencing of antibody regions in rhesus macaques to support HIV vaccine research, focusing on antibody genetics and data sharing.
Description
This project aims to continue genomic sequencing of the antibody region in populations of rhesus monkeys used in HIV vaccine studies, contributing to a database that provides these data to the scientific community. The research focuses on understanding antibody genetics to improve HIV vaccine strategies, including the development of broadly neutralizing antibodies (bNAbs). The study involves characterizing immunoglobulin (IG) haplotype diversity in rhesus macaques, optimizing protocols, and developing tools for data analysis and community access.