Award
NIH Reporter #5R01HL176879-02
Optimal physical activity timing and 24-hour activity composition for prevention of hypertensive disorders of pregnancy
Recipient
Kaiser Foundation Research Institute
Award Amount
$719,315.00
Ceiling
$719,315.00
Awarded
August 18, 2026
Identifier
5R01HL176879-02
A longitudinal study investigating how timing and intensity of physical activity during pregnancy affect the risk of hypertensive disorders, using data from 1,050 pregnant women and electronic health records to guide future guidelines and interventions.
Description
This project explores physical activity timing and intensity and optimal 24-hour activity compositions at multiple pregnancy timepoints for reducing hypertensive disorders of pregnancy (HDP) risk. It leverages Kaiser Permanente Northern California’s diverse population and electronic health records, along with 24-hour accelerometry, to conduct a longitudinal cohort study of 1,050 pregnant women from early pregnancy through delivery. The study aims to determine associations of physical activity timing and intensity with HDP risk and identify optimal 24-hour activity compositions to inform clinical and public health guidelines.